Gregory P. Donaldson  👋

Postdoc

Laboratory of Mucosal Immunology (Mucida Lab)

Rockefeller University

gdonaldson@rockefeller.edu

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I am a microbiologist studying the molecular symbiosis between gut bacteria and their hosts. An absorptive epithelial lining of the gut is the fundamental structure defining all animals throughout evolutionary history. Intestinal epithelial barriers are typically colonized by a community of bacterial symbionts (microbiota) that engage in nutrient exchange with the host to their mutual benefit. While this interface has been extensively studied in terms of antimicrobial factors and microbial pathogenesis, most bacteria-epithelial interactions are benign. By studying processes of molecular symbiosis that maintain health, we may uncover new strategies to prevent disease at its cellular origin, as well as inform the design and deployment of microbe-based therapeutics.

#microbiome #epithelial #IgA #cancer